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Yashoda Hospitals Hyderabad on Mond6 announced the successful treatment and recovery of Shreya Thakur, a 14-year-old female patient, who presented with a rare and complex case of Toxic Epidermal Necrolysis (TEN), considered to be a drug-induced condition brought on by lamotrigine and oxcarbazepine.

This challenging case was further complicated by sepsis, making her recovery an exemplary medical achievement, the hospital said in a release here. Shreya Thakur, who had a history of epilepsy and recent medication changes to Lamotrigine and Oxcarbazepine, was admitted to an outside hospital with a fever and severe bullous eruptions on her body.

She subsequently developed bilateral lung consolidation, sepsis, and shock, necessitating intubation.
Recognizing the complexity of her condition, the outside hospital referred her to Yashoda Hospitals for advanced evaluation and management. The medical team at Yashoda Hospitals, led by Dr. L. Sudarshal Reddy, Senior Consultant Physician, initiated comprehensive care upon Miss Shreya Thakur’s arrival.
The treatment journey involved intensive care, intravenous antibiotics, potassium correction, antiepileptic medications, and other supportive measures.

Her condition improved gradually, allowing for extubation, the management of skin rashes with the assistance of plastic surgery, and a successful weaning off of oxygen support.
Blood cultures indicated the presence of Acinetobacter baumannii growth, prompting the administration of appropriate antibiotics, including Inj. Minocycline.

Subsequent blood cultures showed no growth after 48 hours, affirming the effectiveness of the treatment.
“Shreya’s case demonstrates the power of collaborative medical expertise,” stated Dr. L. Sudarshala Reddy.
Thakur is being discharged in a stable condition with prescribed medications and medical advice for continued care.